Skip to content

What is Terbinafine?

Antifungal Treatments

There are TWO main classes of antifungal agents for the treatment of fungal skin infections:

Class of antifungal agentAllylamineAzole
Example of antifungalTerbinafineClotrimazole
Mode of actionFungicidal
Fungal cell death
Fungal cell growth arrest

Both classes of antifungal agents work by interfering with fungal cell wall synthesis,

Fungicidal agents, such as terbinafine kills the fungal organism and has a shorter treatment time and often higher cure rates compared to fungistatic agents.

Benefits of Terbinafine

Allylamines (such as terbinafine)

  • Short treatment course
  • Low relapse rate

The fungicidal action of terbinafine allows it to bind to corneocytes (cells that make up the outermost layer of the epidermis) and remain in the outermost layer of the epidermis creating a ‘reservoir effect’, thus reducing the treatment course and provides lasting protection against the recurrence of symptoms.